For me, it would be GLaDOS.
Portal 2 spoiler
She deleted the one remaining human part of herself because it was just too much to deal with. She releases you at the end of Portal 2 as a path of least resistance measure because “killing you is hard.”
What about you, what is your favorite media villain?
Idk who my all time favorite is, but I just finished rewatching Clone Wars and man I had forgotten how much I liked Hondo Ohnaka
Maul: “Filth! You will pay for your insolence!”
Hondo: “Insolence?! We are pirates! We don’t even know what that means.”
also the line right before this when Hondo says “who are these horny headed maniacs”
They should hijack a library