I can explain regarding opioids. The human body produces it’s own opioids in small amounts, which dock to specific brain receptors (those work like key & lock), which makes us feel good by releasing dopamine and has a slew of other body-wide consequences like changes in core body temperature and slowing down the digestive tract.

Using opiates floods those receptors with more and more fitting keys that stay in the lock for far longer than the body’s own opioids. This is an high that is not reproducible by anything else. But it has the consequence that now the body reduces the amount of receptors/keyholes because the reaction was so intense, creating tolerance.

After a short while of usage, the bodys own opioids are not enough anymore to create a meaningful response - the external opioid addition has completely overwhelmed the miniscule potiental of the bodys own signal cascade. Not adding opioids now leads to withdrawal - the gut starts working like crazy and cramps painfully, you feel cold the entire time, you are depressed, your nose runs constantly, and all this time your whole body and mind scream to get the next dose.

It takes a very careful approach to get the opioid system back into balance. Substitution works as an external opioid regulation mechanism, where the “keys” don’t fit the lock perfectly, but also get “stuck” there for a while, leading to a lower activation and blocking out any additional opioids from doing their work. After stabilizing, it can take pretty long to reduce the substitution to a level where withdrawal is easily manageable, so that the natural system can take back it’s function. People who are predisposed for addictive behaviour might even just keep taking the substitution to prevent relapse.

Anyone acting this way has very obvious psychiatric issues. Damn, anyone who infantilizes himself this consequently is probably not really fit to stand trial.

Was it a confirmed direct hit? Might have been that the Apache was on drone defense duty and the Shahed shrapnel after interception got an lucky/unlucky hit - that’s actually much more likely than succeeding in hitting an Apache with an Shahed on purpose. Shaheds are pretty bad at hitting fast moving targets - they mainly get preprogrammed paths to follow. There are remote control variants in Russia to enable live tracking of faster targets, but even then an Apache has a huge maneuverability advantage, and Shaheds are slow in comparison to most anti-air missiles.

Sadly, it’s been shown that in general, cognitive performance takes a nosedive after hour 8 of mentally straining work. Of course not everyone is the same, but the long hours especially in the medical field (where everyone involved should know better) should be reduced and allow for a level of rest appropriate to the potential cost of mistakes.

It’s their hatred that takes the actions of a single person and applies the same judgement over everyone who doesn’t look white enough or doesn’t agree with them (“put your phones away or you’re next”). The attempted homicide is just a welcome excuse for the shit they do in spite of the wishes of the victims family. They’re filth, and for once the water cannons were aimed at the right targets, so that innocent people are protected from those dipshit Nazi arsonists. May their socks stay wet for an entire year.

I’ve been playing Vultures: Scavengers of Death, a turn-based Resident Evil style game. I like the atmosphere, but it’s been a bit of a “best of bugs”-festival (stuff like 0 Bullet stacks that crash the game when clicking on them in the inventory, softlocks when the train you should enter disappears when leaving/reentering the room and all the good things).

I also invested in getting the addons my Rimworld was missing, and i am currently bashing my head against my inability to play it without mods - i even accepted just installing a collection instead of rolling my own, and after 17 minutes of start time it just crashed, which means reverifying the 1220 installed mods.

I started with Lutris, and dropped it about a year ago. Lutris tries too many things at once, and badly. If i want emulation, i prefer stuff like Retrodeck, which is a one-stop-shop for this usecase, and Heroic now can handle the same stuff as Lutris regarding PC games with less fiddling and an actually usable UI.

Faugus Launcher is my new light-weight addition, but it’s place is not yet secure on my system. I would LOVE for Playnite to get ported over to Linux, it’s the only piece of software i really, really miss from my Windows times.

Edit: Woohoo! https://github.com/JosefNemec/Playnite/issues/59

I’m planning to move to Linux in 2026 after P11 is done, and since Playnite is my personal blocker for the move, I will try to make some Linux version in 2026. Definitely not fully featured version on parity with Windows version of P11, and probably desktop mode only, but something daily drivable with Linux specific features (Wine/Proton integration for example). If that goes well, I’ll start looking into P11 Avalonia porting proper say I mentioned in previous update.

Avoid Wine 10, sometime in the last 6 months the same installers that worked before stopped doing their thing, those that use a multi-step-process during extraction simply fail. Using Proton-GE-9-27 i have a 100% success rate over the last months.

IIRC, only specific pellets that need a second pass to make their nutrients available.

But at least they can’t vomit, so they don’t have to deal with that.

There is a nice german word for such thinking. It’s “Vollkasko-mentalität” - Vollkasko is car insurance which covers everything + mentality.

I also find it funny that any existing smartphones have to work in this system too. I’d like to see the performance of any filter technology on an Android 4 based device that hasn’t seen an update or an replacement battery for decades. And what about feature phones?

I’d say let them catapult themselves back into analog times, it’ll be fun to watch when they realize that filtering that requires opening letters like back in East Germany.

Because on a vocal minority (which is right in most cases when referring to non-local LLMs) and a large majority of people who use AI without thinking about it, just liking the nice sycophantic chatbot without having to pay the real cost yet. A lot of money is invested to make sure the sheep stay silent.

Which does not prevent this type of injury, it only increases the chance if you use it, but you might just get unlucky with a homerun living downwind from a stadium lol

Urethritis - Less common causes include irritating chemicals or injury from a urinary catheter

Tell me about it. Catheter injury can also cause prostatitis - that’s something they don’t tell you beforehand. After a major surgery, i had to fight this shit 2 years afterwards, caused by that damn catheter. Now at least i have my peace, but that was a very unpleasant experience. -213EC1B2/5 stars.

hope you enjoyed it!

And God shuffled his feet.

The album name has been burned into my brain just like burn-in on an old LCD happens.

I agree on that even if they need two different platforms, they should cooperate regarding infrastructure - The french fighter is not worth much if it isn’t supplemented by unmanned support these days. A drone strike force able to support/protect a french nuclear capable fighter that is also able to do it’s own thing is probably the way to go.

For his part, Merz has openly questioned whether developing a manned sixth-generation fighter jet still made sense for his country’s air force, and said Germany did not need a nuclear-capable jet that could ​land on an aircraft carrier.

He’s pretty right about that. France wants something able to project power, which is not the main interest of Germany. There are two differing objectives, which need two different platforms.

doesn’t make sense to single out any user over there, they are all bootlickers for the kinds of Putin and Xi. Funnily enough, this would make them prime MAGA material too lol

Hungary has taken some big positive steps lately, which made me very happy for my european neighbors! It’s not all doom and gloom. Armenia also kept their distance from the russians, much to my delight.

lemmygrad.ml is not federated with many, many other instances exactly because of their authoritarian BS, including dbzer0.com. you might need to log out and visit lemmygrad.ml directly.

If you want the general idea you can also just take a look at [email protected] and search for lemmy.ml.